Ora-Plus Oral Suspending Vehicle 473ml

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Ora-Plus Oral Suspending Vehicle 473mL

Ora-Plus is a pharmacist-trusted oral suspending vehicle formulated to make smooth, uniform liquid suspensions from crushed tablets or bulk powders. Its thixotropic base flows easily when shaken or poured, then thickens at rest to help keep insoluble particles evenly dispersed—supporting dose uniformity, reduced settling, and better patient acceptability. Unflavoured and designed to pair with a separate sweetening/flavouring vehicle, Ora-Plus is ideal for paediatric, geriatric, dysphagia and feeding-tube patients who need customised oral liquids prepared under professional guidance.

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Active/Key Excipients

(Functional ingredients; see product label for the complete list and exact amounts.)

• Structured cellulose/xanthan gum system – creates a thixotropic gel that suspends particles and minimises caking.

• Carboxymethylcellulose sodium / microcrystalline cellulose – viscosity and mouthfeel; helps uniform redispersion.

• Buffering salts & pH adjusters – maintain a pH suitable for many actives and flavours.

• Preservatives (e.g., parabens) – help protect the vehicle from microbial growth.

• Purified water – aqueous base.

• Antifoam (e.g., simethicone) – improves handling and pouring.

Alcohol-free; typically sugar-free and dye-free. Always check the label for excipients and allergens.

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Reasons to Use

• Extemporaneous compounding of oral suspensions when a commercial liquid is unavailable.

• Dose uniformity and patient-friendly texture with reduced sedimentation.

• Unflavoured base designed to be combined with a separate sweetening/flavouring vehicle.

• Suitable for paediatric/geriatric use and patients with swallowing difficulties (as directed).

• Consistent viscosity that re-suspends easily with shaking.

Reasons Not to Use

• Not a medicine and not for parenteral, ophthalmic, or inhalation use.

• Do not use in patients with known hypersensitivity to any excipient (e.g., parabens).

• Use with caution in neonates/infants or special populations per professional judgement.

• Do not substitute for professional stability data—some actives may be incompatible or require different vehicles.

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Advantages

• Thixotropic: pours easily, thickens at rest for superior suspension.

• Neutral taste aids palatability when paired with a flavouring vehicle.

• Sugar-free, alcohol-free base; typically dye-free.

• Compatible with many APIs and flavouring syrups; easy to shake and re-disperse.

• Large 473mL bottle suited to prescription volumes and repeat compounding.

Disadvantages

• Contains preservatives (parabens)—not suitable for everyone.

• Final stability and beyond-use dating depend on the API and compounding method.

• Some drugs may still settle over time and require vigorous shaking.

• May not mask taste without a separate flavouring vehicle.

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Frequently Asked Questions (FAQ)

Q: What exactly is Ora-Plus?
A: A professional oral suspending vehicle used to compound liquid suspensions from tablets or powders. It provides the viscosity and particle-wetting properties needed for a smooth, uniform product.

Q: How do I use it in compounding?
A: In general: finely powder the API/tablets; wet with a small amount of Ora-Plus to make a smooth paste; use geometric dilution with additional Ora-Plus; add your chosen sweetening/flavouring vehicle; bring to final volume; label “Shake well” and assign a beyond-use date per current standards and stability data.

Q: What ratio should I use with a flavouring vehicle?
A: Many formulas use approximately 1:1 (Ora-Plus : flavouring vehicle), but the exact ratio depends on the API, desired sweetness, and target viscosity. Follow your pharmacy’s validated recipe.

Q: Is Ora-Plus sweet or flavoured?
A: No—it is unflavoured. Combine with a compatible sweetening/flavouring vehicle to improve taste.

Q: Do I need to refrigerate compounded suspensions made with Ora-Plus?
A: Storage conditions depend on the API and stability data. Follow your pharmacy’s protocol and label instructions. The unopened vehicle itself is typically stored at controlled room temperature; do not freeze.

Q: How long is the beyond-use date (BUD)?
A: The BUD is determined by current compounding guidelines and API-specific stability references. Without API stability data, default timeframes may apply per professional standards.

Q: Is it safe for feeding tubes?
A: Many pharmacists compound tube-friendly suspensions with Ora-Plus because of its fine particle dispersion, but tube compatibility should be confirmed for each API and patient situation.

Q: Are there allergens?
A: Check the label for parabens and other excipients. Do not use if the patient is allergic to any ingredient.

Q: Any handling tips?
A: Shake the vehicle before use, record lot/expiry in the compounding log, and counsel patients to shake the finished suspension vigorously before each dose.

Q: Can I colour or sweeten the final product?
A: Yes—add a compatible flavouring/sweetening vehicle per your formula. Verify pH and compatibility with the API.

ALWAYS READ THE LABEL ON THE PRODUCT AND FOLLOW THE DIRECTIONS FOR USE UNLESS DIRECTED BY YOUR HEALTHCARE PROFESSIONAL.

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