Hyalase Ampoules 1500 IU Box of 5
Available Online Only
Hyalase Ampoules 1500 IU Box of 5
- Product type: Medicine — Registered (AUST R)
- Used for: a Schedule 4 injectable hyaluronidase used by registered healthcare practitioners as an adjuvant to increase tissue absorption of injected fluids
- ARTG listing: AUST R 27749
- Australian sponsor: Sanofi-Aventis Australia Pty Ltd
- Schedule: S4 (Prescription Only)
- Pack size: 5 × 1500 IU ampoules
- Last reviewed: 29 May 2026
Product specification
| ARTG ID | 27749 |
|---|---|
| Listing / registration number | AUST R 27749 |
| Product type | Medicine — Registered (AUST R) |
| Australian sponsor | Sanofi-Aventis Australia Pty Ltd |
| Dosage form | Lyophilised powder for injection (ampoule) |
| Route of administration | Subcutaneous / Intramuscular (by registered healthcare practitioner) |
| Pack size | 5 × 1500 IU ampoules |
| Active ingredients | Hyaluronidase 1500 IU per ampoule (lyophilised powder for reconstitution) |
| Schedule | S4 (Prescription Only) |
| Storage | Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children. |
About this product
Hyalase Ampoules 1500 IU Box of 5 is a Schedule 4 injectable hyaluronidase used by registered healthcare practitioners as an adjuvant to increase tissue absorption of injected fluids. Supplied in Australia by Sanofi-Aventis Australia Pty Ltd. Use it in accordance with the carton instructions and your healthcare professional's advice.
About the active
Hyaluronidase 1500 IU
Hyaluronidase is an enzyme that catalyses the hydrolysis of hyaluronic acid, a major component of the extracellular matrix. By transiently reducing the viscosity of the interstitial gel, hyaluronidase increases the diffusion of co-administered fluids through tissue spaces.
The pharmaceutical product is a defined-potency lyophilised powder reconstituted prior to injection. Each ampoule provides 1500 IU of hyaluronidase activity.
Indicated as an adjuvant to enhance dispersion and absorption of injected fluids (subcutaneous fluid administration — hypodermoclysis); as an adjuvant in subcutaneous urography to improve absorption of contrast media; as an adjuvant in ophthalmology with local anaesthetics in eye surgery; and in the management of selected extravasation events. Use is restricted to administration by a registered healthcare practitioner.
Safety: Schedule 4 (Prescription Only). Contraindicated in known hypersensitivity to hyaluronidase or bee venom. Not to be applied directly to infected or acutely inflamed areas, or used to reduce the swelling of bites and stings, unless directed by a specialist. Anaphylactic reactions have been reported rarely — appropriate resuscitation facilities must be available.
Indications
The following indications are recorded on this product's ARTG entry:
- Adjuvant to increase the rate of absorption of parenterally administered fluids (e.g. subcutaneous infusion of fluids — hypodermoclysis) in adults and children
- Adjuvant in subcutaneous urography to improve absorption of contrast media
- Adjuvant in ophthalmology for use with local anaesthetics in eye surgery
- Management of selected extravasation events
Directions for use
Prescription only — for administration by a registered healthcare practitioner only, in accordance with the Product Information. Reconstitute and dose as per the Product Information.
Warnings and important information
- Always read the label and follow the directions for use.
- If symptoms persist, talk to your healthcare professional.
- Discuss with your pharmacist or doctor before use during pregnancy or breastfeeding.
- Keep out of reach of children.
- Do not use after the expiry date printed on the pack.
- Stop use and seek advice if any unexpected reaction occurs.
Storage
Store below 30°C in a dry place, away from direct sunlight. Keep the original packaging closed. Keep out of reach of children. Do not use after the expiry date printed on the pack.
Frequently asked questions
What is Hyalase Ampoules 1500 IU used for?
Hyalase Ampoules 1500 IU is a Schedule 4 injectable hyaluronidase used by registered healthcare practitioners as an adjuvant to increase tissue absorption of injected fluids. It is supplied in Australia by Sanofi-Aventis Australia Pty Ltd. Refer to your pharmacist or doctor for advice on whether the product is suitable for you.
How does Hyalase Ampoules 1500 IU work?
The active in Hyalase Ampoules 1500 IU is described in detail under 'About the active' above. The mechanism of action is summarised there in plain English.
What are the active ingredients in Hyalase Ampoules 1500 IU?
Hyalase Ampoules 1500 IU contains Hyaluronidase 1500 IU per ampoule (lyophilised powder for reconstitution). The full active panel is shown in the Product Specification table above.
How do I take Hyalase Ampoules 1500 IU?
Prescription only — for administration by a registered healthcare practitioner only, in accordance with the Product Information. Reconstitute and dose as per the Product Information.
What are the possible side effects?
Refer to the Consumer Medicine Information leaflet supplied with the pack and to your pharmacist for the full side-effect profile. Stop use and seek advice if any unexpected reaction occurs.
Can I take this with my other prescription medicines?
Several common medicines interact with Hyalase Ampoules 1500 IU. Bring the pack to your pharmacist and ask them to check it against your current medicines list before starting.
Is this suitable during pregnancy or breastfeeding?
Use during pregnancy or breastfeeding is not recommended without professional advice. Refer to the carton and confirm with your pharmacist or doctor.
What if I miss a scheduled injection?
Hyalase Ampoules 1500 IU is administered by a registered healthcare professional on the schedule your doctor has prescribed. If you miss an appointment, contact your prescriber to reschedule — do not attempt to make up missed doses by giving extra at the next appointment.
Is this medicine TGA approved?
Yes. Hyalase Ampoules 1500 IU is a Registered (AUST R) medicine on the Australian Register of Therapeutic Goods, individually evaluated by the TGA for safety, quality and efficacy. The AUST R number is 27749 — you can verify the entry at tga.gov.au/resources/artg/27749.
Where is it manufactured?
Hyalase Ampoules 1500 IU is supplied in Australia by Sanofi-Aventis Australia Pty Ltd.
This information is general in nature and is not a substitute for professional medical advice. If you have questions about whether Hyalase Ampoules 1500 IU is right for you, speak with your pharmacist or doctor. For 24-hour health advice in Australia, call Healthdirect on 1800 022 222. For poisoning enquiries, call the Poisons Information Centre on 13 11 26.
Sources
- Australian Register of Therapeutic Goods (ARTG) — entry for this product. tga.gov.au/resources/artg
- Therapeutic Goods Administration — Permissible Indications Determination and Therapeutic Goods (Therapeutic Goods Advertising Code) Instrument 2021. tga.gov.au
- Healthdirect Australia — general consumer health information. healthdirect.gov.au
- Manufacturer carton and Consumer Medicine Information (where supplied).
ALWAYS READ THE LABEL ON THE PRODUCT AND FOLLOW THE DIRECTIONS FOR USE UNLESS DIRECTED BY YOUR HEALTHCARE PROFESSIONAL.
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(Product SKU 226373)
| SKU | 226373 |
| Barcode # | 9312319130516 |
| Shipping Cubic | 0.000164000m3 |
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