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Neo B12 Injection 1000mcg/1ml Box of 3. Treatment of vitamin B12 deficiency, including pernicious anaemia, dietary B12 deficiency, and B12 deficiency associated

The estimated expiry for this product is 09/2027. It was last checked and updated on 22 MAY 26. This is an indicative expiry based upon the last stock check and may vary at the time of supply. Images and information supplied on the website are for representation purposes only. Actual product may differ from images shown. Please contact us to verify if you are looking for a specific packaging or formulation prior to making an order. We will always endeavour to supply the latest product packaging and formulations from the manufacturer with the longest expiry possible.

Neo B12 Injection 1000mcg/1ml Box of 3

Key facts

Product type: Medicine — Registered (AUST R)
Used for: a Schedule 4 injectable vitamin B12 (hydroxocobalamin) used for the treatment of vitamin B12 deficiency under medical supervision
ARTG listing: AUST R 121709
Australian sponsor: Pfizer Australia Pty Ltd
Schedule: S4 (Prescription Only)
Pack size: 3 × 1 mL glass ampoules
Last reviewed: 29 May 2026

Neo B12 Injection 1000mcg/1ml Box of 3 is a Schedule 4 injectable vitamin B12 (hydroxocobalamin) used for the treatment of vitamin B12 deficiency under medical supervision. Refer to the carton and to your pharmacist or doctor for advice on whether this product is right for you.

Product specification

ARTG ID	121709
Listing / registration number	AUST R 121709
Product type	Medicine — Registered (AUST R)
Australian sponsor	Pfizer Australia Pty Ltd
Dosage form	Solution for injection (ampoule)
Route of administration	Intramuscular / Deep subcutaneous (by registered healthcare professional)
Pack size	3 × 1 mL glass ampoules
Active ingredients	Hydroxocobalamin chloride 1000 micrograms per 1 mL ampoule
Schedule	S4 (Prescription Only)
Storage	Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.

About this product

Neo B12 Injection 1000mcg/1ml Box of 3 is a Schedule 4 injectable vitamin B12 (hydroxocobalamin) used for the treatment of vitamin B12 deficiency under medical supervision. Supplied in Australia by Pfizer Australia Pty Ltd. Use it in accordance with the carton instructions and your healthcare professional's advice.

About the active

Vitamin B12 — Hydroxocobalamin

Vitamin B12 is a water-soluble vitamin essential for normal red blood cell formation, neurological function and DNA synthesis. It is not produced by the human body and must be obtained from the diet (animal-derived foods) or via supplementation. Vitamin B12 deficiency leads to megaloblastic anaemia and, if untreated, irreversible neurological injury.

This injection supplies hydroxocobalamin, a pharmaceutical form of vitamin B12 that is well retained in body stores, making it suitable for monthly maintenance dosing once stores are replenished. Each 1 mL ampoule contains 1000 micrograms of hydroxocobalamin chloride.

Indicated for the treatment of vitamin B12 deficiency, including pernicious anaemia, dietary B12 deficiency, and B12 deficiency associated with malabsorption syndromes; for the prevention and treatment of confirmed cyanide poisoning; and for tobacco amblyopia and Leber's optic atrophy.

Safety: Schedule 4 (Prescription Only). Administered by a registered healthcare professional in accordance with the Product Information. Dose and frequency are individualised — typical loading and maintenance schedules are detailed in the PI. Discuss with the prescriber before use during pregnancy or breastfeeding, in Leber's hereditary optic neuropathy, or if you take medicines that affect vitamin B12 absorption (e.g. metformin, long-term proton pump inhibitors).

Indications

The following indications are recorded on this product's ARTG entry:

Treatment of vitamin B12 deficiency, including pernicious anaemia, dietary B12 deficiency, and B12 deficiency associated with malabsorption syndromes
Prevention and treatment of confirmed cyanide poisoning
Tobacco amblyopia and Leber's optic atrophy

Directions for use

Prescription only — administered by a registered healthcare professional in accordance with the Product Information. Dose and frequency are individualised.

Warnings and important information

Always read the label and follow the directions for use.
If symptoms persist, talk to your healthcare professional.
Discuss with your pharmacist or doctor before use during pregnancy or breastfeeding.
Keep out of reach of children.
Do not use after the expiry date printed on the pack.
Stop use and seek advice if any unexpected reaction occurs.

Storage

Store below 30°C in a dry place, away from direct sunlight. Keep the original packaging closed. Keep out of reach of children. Do not use after the expiry date printed on the pack.

Frequently asked questions

What is Neo B12 Injection 1000mcg/1ml used for?

Neo B12 Injection 1000mcg/1ml is a Schedule 4 injectable vitamin B12 (hydroxocobalamin) used for the treatment of vitamin B12 deficiency under medical supervision. It is supplied in Australia by Pfizer Australia Pty Ltd. Refer to your pharmacist or doctor for advice on whether the product is suitable for you.

How does Neo B12 Injection 1000mcg/1ml work?

The active in Neo B12 Injection 1000mcg/1ml is described in detail under 'About the active' above. The mechanism of action is summarised there in plain English.

What are the active ingredients in Neo B12 Injection 1000mcg/1ml?

Neo B12 Injection 1000mcg/1ml contains Hydroxocobalamin chloride 1000 micrograms per 1 mL ampoule. The full active panel is shown in the Product Specification table above.

How do I take Neo B12 Injection 1000mcg/1ml?

Prescription only — administered by a registered healthcare professional in accordance with the Product Information. Dose and frequency are individualised.

What are the possible side effects?

Refer to the Consumer Medicine Information leaflet supplied with the pack and to your pharmacist for the full side-effect profile. Stop use and seek advice if any unexpected reaction occurs.

Can I take this with my other prescription medicines?

Several common medicines interact with Neo B12 Injection 1000mcg/1ml. Bring the pack to your pharmacist and ask them to check it against your current medicines list before starting.

Is this suitable during pregnancy or breastfeeding?

Use during pregnancy or breastfeeding is not recommended without professional advice. Refer to the carton and confirm with your pharmacist or doctor.

What if I miss a scheduled injection?

Neo B12 Injection 1000mcg/1ml is administered by a registered healthcare professional on the schedule your doctor has prescribed. If you miss an appointment, contact your prescriber to reschedule — do not attempt to make up missed doses by giving extra at the next appointment.

Is this medicine TGA approved?

Yes. Neo B12 Injection 1000mcg/1ml is a Registered (AUST R) medicine on the Australian Register of Therapeutic Goods, individually evaluated by the TGA for safety, quality and efficacy. The AUST R number is 121709 — you can verify the entry at tga.gov.au/resources/artg/121709.

Where is it manufactured?

Neo B12 Injection 1000mcg/1ml is supplied in Australia by Pfizer Australia Pty Ltd.

When to seek further advice

This information is general in nature and is not a substitute for professional medical advice. If you have questions about whether Neo B12 Injection 1000mcg/1ml is right for you, speak with your pharmacist or doctor. For 24-hour health advice in Australia, call Healthdirect on 1800 022 222. For poisoning enquiries, call the Poisons Information Centre on 13 11 26.

Sources

Australian Register of Therapeutic Goods (ARTG) — entry for this product. tga.gov.au/resources/artg
Therapeutic Goods Administration — Permissible Indications Determination and Therapeutic Goods (Therapeutic Goods Advertising Code) Instrument 2021. tga.gov.au
Healthdirect Australia — general consumer health information. healthdirect.gov.au
Manufacturer carton and Consumer Medicine Information (where supplied).

ALWAYS READ THE LABEL ON THE PRODUCT AND FOLLOW THE DIRECTIONS FOR USE UNLESS DIRECTED BY YOUR HEALTHCARE PROFESSIONAL.

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(Product SKU 244155)